Jack of Fables is a spin-off comic book series of Fables written by Bill Willingham and Matthew Sturges and published by DC Comics' Vertigo imprint. The story focuses on the adventures of Jack Horner, a supporting character in the main series, and takes place after his exile from Fabletown in the story-arc Jack Be Nimble. The idea for the spin-off comic came when editor Shelly Bond suggested to put Jack in a separate comic after Willingham planned to write him off the series.

While Jack of Fables focused on the eponymous Jack Horner, the spin-off also allowed Willingham and Sturges to expand upon the Fables Universe and add more elements like other literary characters and anthropomorphic personifications in the series. A preview of its first issue was shown in Fables #50, and the series itself debuted in July 2006. It ran for 50 issues from July 2006 to March 2011, and received positive reception from critics and fans alike during its release, though overtime would be criticized because of the main character's abhorrent sociopathy. In 2007, it was nominated for numerous Eisner Awards and won Best Lettering for Todd Klein and Best Cover Artist for James Jean.