It’s well documented that Deadpool has a manic motormouth and a healing factor that makes him virtually unkillable. As a result, battling him is an experience that would try the patience and focus of just about anyone. Unfortunately for him, there’s one individual infamous throughout the Marvel Universe for his laser focus and ability to hunt a target until it’s destroyed. He also happens to know what it’s like to fight against — and reluctantly alongside — Deadpool. This April, Wade Wilson finds himself in Frank Castle’s crosshairs, as Fred Van Lente and Pere Perez kick off the five issue “Deadpool Vs. Punisher” miniseries.

This is no simple slugfest between two of Marvel’s murderous anti-heroes, though. Once the opening shots are fired, the conflict will escalate into a worldwide melee, as Frank and Wade battle not only each other, but an army of villains out for their blood.