The gamma radiation that mutated the Abomination's body fortified his cellular structure and added, from some as yet unknown source, over 800 pounds of bone marrow and tissue to his body. Unlike the Hulk's, the Abomination's transformation has proved stable; he cannot change back and forth between his human state and his superhuman state.

Superhuman Strength: The Abomination possesses vast superhuman strength, enabling him to lift somewhere in excess of "Class 100". Although the Abomination's strength surpasses that of certain classic incarnations of the Hulksuch as Mr. Fixit (Class 70) or the Green Savage Hulk (Class 90), the Abomination's strength does not fluctuate like the Hulk's. Hence, while the Abomination may be stronger than a "calm" Hulk, when enraged Hulk's strength level rapidly reaches and exceeds the Class 100+ level possessed by Blonsky. The Abomination's great strength also extends into the highly developed and powerful muscles of his legs, enabling him to leap great distances.

Superhuman Stamina: The Abomination's highly advanced musculature produces vastly less fatigue toxins during physical activity than the musculature of an ordinary human. He is capable of physically exerting himself at peak capacity for several days before the build up of fatigue toxins in his blood begins to impair him.

Superhuman Durability: In addition to great strength, the Abomination's bodily tissues are substantially harder and more resistant to injury than the tissues of an ordinary human. The Abomination's skin is capable of withstanding great heat without blistering, great cold without freezing, and great impacts without injury. His body is also capable of withstanding tremendous impact forces, such as artillery shells and powerful energy blasts, without sustaining injury.

Regenerative Healing Factor: Despite his great physical resilience, it is possible to injure him. However, he possesses an accelerated healing factor similar to that possessed by the Hulk. As a result, he is capable of regenerating great amounts of damaged or destroyed tissue with much greater speed and efficiency than an ordinary human. While the full extent of his healing powers are unknown they are inferior to those of the Hulk since the Hulk's healing powers, much like his strength, increases as he becomes angrier. The Abomination is also immune to all known Earthly diseases and infections.