Long ago, the demon Zarathos began building a tremendous power base for himself. His penchant for human souls led him into conflicts with foes such as the Blood cult and the vile Mephisto, who saw Zarathos as a rival. Mephisto ultimately tricked and enslaved Zarathos, rendering the demon amnesiac and trapping him in various mortal forms over many years.

This torture eventually dovetailed with another pastime of Mephisto's - the search for the Medallion of Power, a mystical artifact crafted by the Blood that housed the essence of the original Spirits of Vengeance. The medallion had been broken into shards and embedded into the spiritual bloodline of two families. One of these bloodlines, the Kales, attracted Mephisto's attention in the 18th century when Noble Kale's shard of the Medallion transformed him into a Spirit of Vengeance, the Ghost Rider. Mephisto failed to corrupt Noble at this time, but he kept track of the Kale clan from then on, watching as Noble manifested in the firstborn of every generation. John Blaze was born into a world of motorcycle grease and cheering crowds. The son of Barton Blaze and Naomi Kale, Johnny spent his early years in the Quentin Carnival, where his parents starred in a stunt show with Craig "Crash" Simpson. His idyllic home life ended abruptly, however, when Naomi abandoned John, taking his younger siblings - Barbara and Daniel - with her. Naomi's decision to leave had been difficult, but she felt it was necessary because of the family curse. She feared that her own firstborn would suffer in the same way that she had, so she left him behind and placed her other children in the care of a woman named Francis Ketch.