The Super-Soldier Serum (SSS) metabolized and permanently enhanced all of Rogers' bodily functions to beyond the peak of human potential. Dr. Reinstein described this potential as being "the next step in human evolution," while still remaining completely human but often called the "Perfect Man." The secret of the SSS formula was lost upon Dr. Erskine's death.Nick Fury's intel classified him as power level 8.

Artificially Enhanced Physiology: Rogers has no superhuman powers, although as a result of the Super-Soldier Serum, he was transformed from a frail young man into a "perfect" specimen of human development and conditioning. Rogers is as intelligent, strong, fast, agile, and durable as possible for a human being to be without being considered superhuman. The SSS is definite, even if he chose to live an unhealthy lifestyle, none of his abilities would weaken.

Enhanced Strength: Rogers' physical strength is enhanced to the very peak of human potential. Captain America had been seen bench pressing 544 kg/1,200 lbs on each side of the bar, which is consistent with his strength level, as benching is easier than military press lifting. This strength also extends to his legs, enabling him to leap 6m/20ft out in a single bound and 10ft/3m into the air without a running start. He can snap steel handcuffs and chains, and is capable of breaking through wooden walls and steel doors with a single kick.

Enhanced Speed: He can run at speeds of up to a mile in a minute (60 mph).

Enhanced Durability: His bones and muscles are denser and harder and so are amplified to the highest human potential, making him very durable. He is durable enough to the point that if a person beats him with a metal bat stick, the bat would break and Rogers would show little discomfort. This is how he survived other forms of extensive punishment throughout his career such as falls from several stories like when he landed on a car from 2000 feet with no injury.

Enhanced Agility: His agility is greater than that of an Olympic gold medalist. He can coordinate his body with balance, flexibility, and dexterity.

Enhanced Reflexes: Rogers' reflexes border on superhuman level. His reaction speed is 20 kph, which makes it possible for him to dodge gunfire even in point blank range from multiple gunners at the same time.

Enhanced Stamina: Rogers' body eliminates the excessive build-up of fatigue-producing chemicals in his muscles, granting him exceptional endurance and lung capacity. He can exert himself at peak capacity for a hour without any rest and before showing any signs of fatigue.

Accelerated Healing Factor: Rogers' healing speed and efficiency is at the highest limits of human potential, which means he can heal faster than most humans. The white blood cells (WBCs) and the SSS in his body are efficient enough to fight off any microbe, foreign body and others from his body keeping him healthy and immune to all infections, diseases and disorders, also Rogers cannot become intoxicated by alcohol, drugs, or impurities in the air and is immune to terrestrial diseases. He is also immune to hypnosis or gases that could limit his focus. He is genetically perfect.

Enhanced Mental Processing: His mental performance operates in the most efficient and rapid manner possible, and able to processes the world in the most advance and efficient manner. He possesses perfect pattern solving/recognition, limitless information storage/retrieval, perfect perception/observational skills, and logical/philosophical structuring. His mind also processes information quickly, giving him an accelerated learning aptitude. Rogers can also quickly analyze multiple, limitless information streams (e.g., threat assessment) and rapidly respond to changing tactical situations. He possesses an eidetic memory (he never forgets anything and has perfect instant recall), he can read at superhuman speeds, has perfect deductive/reasoning skills, and can intuitively understand what's going to happen and how to deal with it. This enables him to remember any military tactic and apply it to any situation, making him the best tactician in history.

Enhanced Senses: Rogers' senses of sight, hearing, smell, taste, and touch are at the highest possible limits of human potential. He once said that he is able to dodge bullets because he sees faster than them.

Advanced Longevity: The SSS halts Rogers's aging due to perfect cells. Sersi stated he will indefinitely maintain his youth